Table 2. Antibacterial effect of various levels of mixed zinc oxide (ZnO) and copper oxide (CuO) nanoparticles, and florfenicol on Salmonella gallinarum induced infection in broiler in terms of scoring of gross pathological lesions (congestion) of thymus, spleen, and bursa of Fabricius at day 7 and 11 post-infection

Organ Treatments
Control negative Control positive Florfenicol (mg/L) Nanoparticle levels of ZnO and CuO (mg/kg/d)
 T1 (50) T2 (25 + 10) T3 (37.5 + 15) T4 (50 + 20)
S1
 Spleen +++ ++ + ++ ++
 Thymus +++ ++ ++ ++ +
 Bursa of Fabricius ++ + ++ +
S2
 Spleen ++ +
 Thymus ++ +
 Bursa of Fabricius ++
No congestion (−), mild congestion (+), moderate congestion (++), severe congestion (+++). S1 (day 7), S2 (day 11) post-infection sampling.