Table 2. Predicted CDSs involved in Latilactobacillus curvatus CACC879 probiotic potency

Predicted function Gene Start End Length (bp)
CRISPR-associated endonuclease Cas9 31,830 35,723 3,894
Antimicrobial activity-related lysM 1,089,047 1,090,990 1,944
Bacteriocin (Class II)-related blpA c557,488 c558,636 1,149
Lactate synthesis ldh c903,407 c904,384 978
Acid tolerance
 Chaperone protein ClpB clpB 706,508 707,140 633
 Chaperone protein GrpE grpE 1,335,554 1,336,165 612
 ClC family H(+)/Cl(−) exchange transporter eriC 1,148,397 1,149,971 1,575
 Sodium hydrogen exchanger family protein nhaP 1,219,349 1,221,493 2145
 F0F1 ATP synthase subunit A atpB 17,075 17,788 714
 F0F1 ATP synthase subunit B atpF 18,084 18,605 522
 F0F1 ATP synthase subunit C atpE 17,807 18,019 213
 F0F1 ATP synthase subunit delta atpH 18,592 19,134 543
Bile salts tolerance cbh c246,195 C246,716 522
Cell adhesion sotA 73,428 74,090 663
Stress response or protection
 Chaperone protein DnaK dnaK 1,336,202 1,338,037 1,836
 Chaperone protein DnaJ dnaJ 1,338,161 1,339,309 1,149
 Triose-phosphate isomerase tpiA c532,378 c533,133 756
Biosynthesis of vitamin B groups
 Riboflavin (B2) ribF 1,332,094 1,333,047 954
ribT c271,721 c272,089 369
 Cobalamin (B12) pduO 58,751 59,305 555
Modulation of Immune response
 D-alanyl-lipoteichoic acid biosynthesis proteins dltB c220,566 c221,774 1,209
dltD c219,030 c220,298 1,269
 Antioxidant (peroxiredoxin) tpx 565,480 565,974 495
tpxA 780,278 780,601 324
CDSs, coding sequences; bp, base pair; CRISPR, clustered regularly interspaced short palindromic repeats.