Bifidobacterium animalis AHC7 | 2 × 1010 CFU/day | Canine | Young adult dogs with acute diarrhea | Assessment for managing acute diarrhea | Reduced diarrhea compared to placebo group | [22] |
Lactobacillus rhamnosus MP01Lactobacillus plantarum MP02 | 109 CFU/day | Canine | 1 month old puppies | Assessments for preventing gastrointestinal infection in puppies | Significantly increased Lactobacillus and Faecalibacterium in fecalSignificantly increased SCFAs concentration in fecesPrevented gastrointestinal infection | [23] |
Lactobacillus murinus LbP2 | 5 × 109 CFU/day | Canine | Dogs with canine distemper virus (CDV)-associated diarrhea | Assessment of fecal and mental status | Fecal consistency, mental status and appetite were significantly improved | [24] |
Lactobacillus johnsonii CPN23 | 2.3 × 108 CFU/day | Canine | Adult female Labrador dogs | Assessment of nutrient digestibility and fecal fermentative metabolites | Increased crude fiber digestibilityIncreased concentrations of SCFAs in fecesReduction in fecal ammonia concentration | [25] |
Lactobacillus fermentum CCM 7421 | 107–109 CFU/day | Canine | Dogs suffering from gastrointestinal disorder | Assessment of blood samples and composition of the fecal microbiome | Improved total protein, cholesterol and ALT in blood samplesIncreased lactic acid bacteria population and decreased clostridia population along with some of the gram-negative bacterial generaModulate liquid feces to normal consistency (dogs with diarrhea) | [26] |
Lactobacillus fermentum AD1 | 3 mL of 109 CFU/mL | Canine | Healthy dogs | Assessment of blood sample and composition of fecal microbiome | Significantly increased total lipid and total protein in the bloodSignificantly decreased glucose concentration in the bloodstreamSignificantly increased the number of lactobacilli and enterococci in the feces | [27] |
Bifidobacterium animalis B/12 | 1 mL of 1.04 × 109 CFU/mL | Canine | Healthy dogs | Assessment of blood samples and composition of fecal microbiome | Significantly decreased concentration of triglycerides and albumin in blood serumIncreased ALT and ALPIncreased acetic, acetoacetic and valeric acids in feces | [28] |
Lactobacillus johnsonii CPN23 | 108 CFU/mL (0.1 mL/kg BW) | Canine | Adult female dogs | Assessment of blood sample profile | Decreased plasma glucose and cholesterol levelIncreased HDL/LDL ratio | [29] |
Enterococcus faecium DSM 32820 | 109 CFU/day | Canine | Healthy dog | Assessment of blood sample profile | Decreased serum glucose concentration | [30] |
Lactobacillus acidophilus DSM13241 | 2 × 108 CFU/day | Feline | Healthy adult cats | Assessment for improving intestinal health in cats | Increased numbers of beneficial Lactobacillus and L. acidophilus groups in feces and decreased numbers of Clostridium spp. and Enterococcus faecalisDecreased fecal pH and plasma endotoxin concentrations resulting in systemic and immunomodulatory changes in treated cats | [41] |
Enterococcus hirae | 2.85–4.28 × 108 CFU/day | Feline | Kittens | Assessment for preventing atypical Enteropathogenic E. coli (EPEC) in kittens | Highly effective at promoting intestinal colonization and fecal shedding of live E. hirae during administration.Ameliorated the effects of atypical EPEC experimental infection on intestinal function and water loss | [42] |
Enterococcus faecium SF68 | 5 × 109 CFU/day | Feline | Kittens | Effects of Enterococcus faecium strain SF68 supplementation on immune function | The percentage of CD4+ lymphocytes was significantly higher in the treatment group | [43] |