| 1 | Nucleoside and nucleotide biosynthesis | Super pathway of pyrimidine nucleobases salvage | –0.839 | 13.071 | 29.653 | 5.17E-08 | 2.01E-05 |
| 2 | Generation of precursor metabolite and Energy | Pentose phosphate pathway (non-oxidative branch) | –0.824 | 13.094 | 20.929 | 4.77E-06 | 0.000590 |
| 3 | Aromatic compound degradation | Toluene degradation II (aerobic) (via 4-methylcatechol) | 16.045 | 8.814 | 20.366 | 6.40E-06 | 0.000590 |
| 4 | Aromatic compound degradation | Toluene degradation I (aerobic) (via o-cresol) | 16.044 | 8.814 | 20.323 | 6.54E-06 | 0.000590 |
| 5 | Aromatic compound degradation | Catechol degradation I (meta-cleavage pathway) | 18.976 | 8.614 | 20.040 | 7.58E-06 | 0.000590 |
| 6 | Amine and polyamine degradation | Allantoin degradation to glyoxylate III | 14.748 | 7.650 | 16.166 | 5.80E-05 | 0.003504 |
| 7 | Inorganic nutrient metabolism | Nitrate reduction VI (assimilatory) | –7.340 | 9.503 | 16.009 | 6.30E-05 | 0.003504 |
| 8 | Sugar acid metabolism | D-Galactarate degradation I | 8.898 | 4.542 | 14.948 | 0.000111 | 0.005055 |
| 9 | Sugar acid metabolism | D-Glucarate and D-galactarate degradation | 8.898 | 4.542 | 14.841 | 0.000117 | 0.005055 |
| 10 | Aromatic compound degradation | Catechol degradation III (ortho-cleavage pathway) | 28.587 | 8.951 | 14.399 | 0.000148 | 0.005266 |
| 11 | Aromatic compound degradation | Aromatic compounds degradation via β-ketoadipate | 28.588 | 8.951 | 14.386 | 0.000149 | 0.005266 |
| 12 | Aromatic compound degradation | Catechol degradation to β-ketoadipate | 28.386 | 8.809 | 14.070 | 0.000176 | 0.005294 |
| 13 | Fatty acid and lipid biosynthesis | Gondoate biosynthesis (anaerobic) | –0.793 | 13.048 | 13.932 | 0.000190 | 0.005294 |
| 14 | Nucleoside and nucleotide degradation | Adenosine nucleotides degradation II | 9.844 | 9.195 | 13.793 | 0.000204 | 0.005294 |
| 15 | Amino acid degradation | L-Tyrosine degradation I | 12.429 | 8.600 | 13.747 | 0.000209 | 0.005294 |
| 16 | Amine and polyamine degradation | Aromatic biogenic amine degradation (bacteria) | 19.374 | 6.380 | 13.671 | 0.000218 | 0.005294 |
| 17 | Aromatic compound degradation | Super pathway of salicylate degradation | 26.786 | 8.625 | 13.487 | 0.000240 | 0.005497 |
| 18 | Amino acid degradation | L-Leucine degradation I | 12.250 | 9.407 | 13.213 | 0.000278 | 0.005952 |
| 19 | Nucleoside and nucleotide degradation | Purine nucleotides degradation II (aerobic) | 8.390 | 9.712 | 13.129 | 0.000291 | 0.005952 |
| 20 | Sugar acid metabolism | D-Glucarate degradation I | 8.660 | 4.806 | 12.789 | 0.000349 | 0.006781 |
| 21 | Propanoate degradation | 2-Methylcitrate cycle I | 9.695 | 8.674 | 12.467 | 0.000414 | 0.007671 |
| 22 | Aromatic compound degradation | Cinnamate and 3-hydroxycinnamate degradation to 2-hydroxypentadienoate | 32.388 | 8.468 | 12.098 | 0.000505 | 0.008565 |
| 23 | Aromatic compound degradation | 3-Phenylpropanoate and 3-(3-hydroxyphenyl) propanoate degradation to 2-hydroxypentadienoate | 32.388 | 8.468 | 12.092 | 0.000506 | 0.008565 |
| 24 | Amine and polyamine degradation | Allantoin degradation IV (anaerobic) | 13.428 | 6.716 | 11.229 | 0.000805 | 0.013055 |
| 25 | Aromatic compound degradation | Meta cleavage pathway of aromatic compounds | 22.121 | 6.813 | 11.049 | 0.000888 | 0.013810 |
| 26 | Aromatic compound degradation | 3-Phenylpropanoate and 3-(3-hydroxyphenyl) propanoate degradation | 27.451 | 8.520 | 10.975 | 0.000924 | 0.013817 |
| 27 | Secondary metabolite degradation | Engineered pathway: isoprene biosynthesis II (engineered) | 12.333 | 4.357 | 10.740 | 0.001048 | 0.015103 |
| 28 | Nucleoside and nucleotide biosynthesis | Adenosine ribonucleotides de novo biosynthesis | –0.603 | 12.960 | 10.266 | 0.001355 | 0.018827 |
| 29 | Nucleoside and nucleotide biosynthesis | Super pathway of adenosine nucleotides de novo biosynthesis I | –0.693 | 12.986 | 10.005 | 0.001561 | 0.020945 |
| 30 | Aromatic compound degradation | 4-Methylcatechol degradation (ortho cleavage) | 27.042 | 8.601 | 9.596 | 0.001950 | 0.024940 |
| 31 | Aromatic compound degradation | Catechol degradation II (meta-cleavage pathway) | 12.723 | 6.818 | 9.561 | 0.001988 | 0.024940 |
| 32 | Aromatic compound degradation | Protocatechuate degradation II (ortho-cleavage pathway) | 10.463 | 8.309 | 9.373 | 0.002202 | 0.026766 |
| 33 | Sugar nucleotide biosynthesis | CMP-legionaminate biosynthesis I | –8.205 | 8.984 | 9.189 | 0.002434 | 0.028639 |
| 34 | Aromatic compound degradation | Phenylacetate degradation I (aerobic) | 20.830 | 8.727 | 9.138 | 0.002503 | 0.028639 |
| 35 | Aldehyde degradation | Super pathway of methylglyoxal degradation | 21.047 | 6.569 | 8.790 | 0.003029 | 0.033661 |
| 36 | Sugar biosynthesis | Sucrose biosynthesis III | 18.218 | 4.108 | 8.710 | 0.003165 | 0.034199 |
| 37 | Amine and polyamine biosynthesis | Ectoine biosynthesis | 15.114 | 3.587 | 8.505 | 0.003543 | 0.037244 |
| 38 | Amino acid degradation | L-arginine degradation II (AST pathway) | 12.522 | 4.822 | 8.097 | 0.004434 | 0.045390 |
| 39 | Cell structure biosynthesis | Peptidoglycan biosynthesis II (staphylococci) | 4.900 | 9.105 | 7.908 | 0.004922 | 0.048418 |
| 40 | Nucleoside and nucleotide biosynthesis | Super pathway of adenosine nucleotides de novo | –0.697 | 12.922 | 7.853 | 0.005073 | 0.048418 |
| 41 | Cell structure biosynthesis | UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) | –0.739 | 12.817 | 7.781 | 0.005280 | 0.048418 |
| 42 | Secondary metabolite degradation | Sulfoquinovose degradation I | 10.149 | 3.185 | 7.742 | 0.005395 | 0.048418 |
| 43 | Aromatic compound degradation | Catechol degradation to 2-hydroxypentadienoate II | 11.213 | 6.438 | 7.732 | 0.005425 | 0.048418 |
| 44 | Amino acid biosynthesis | L-Lysine biosynthesis II | –2.476 | 11.855 | 7.715 | 0.005477 | 0.048418 |
| 45 | Antibiotic resistance | Polymyxin resistance | 9.731 | 3.860 | 7.668 | 0.005621 | 0.048588 |